The Association between Genetic and Racial Factors in Ethanol Containing Beverages Metabolism and Health Risks in Human

Ethanol containing beverages (alcoholic beverages) are socially acceptable that expected to provide refreshment, satisfaction and stress relief. Common types of ethanol include: wine, beer, syrup. According the World Health Organization, alcohol abuse is a risk factor for high mortality many diseases in humans such as fatty liver, hepatomegaly, cirrhosis, liver cancer, larynx nasopharynx stomach esophageal cancer,… In human, eliminated mainly through metabolism two ways: Oxidative pathway with participation enzymes: dehydrogenase (ADH), aldehyde (ALDH), cytochrome P450 catalase; non-oxidative pathways involving phospholipase acid ethyl ester (FAEE) synthase. Alcohol believed be caused by genetic factors (ADH, ALDH,...), psychological social factors. Single nucleotide polymorphisms (SNPs) genes encoding enzymes involved helped explaining why certain ethnic groups individuals have higher or lower ethanol-related health risks development syndrome. Vietnam, using habit imbued traditional culture. At same time, wine beer already problem causes serious consequences public health, family happiness safety. Meanwhile, concept drinking helps relieve nervous tension common, people still feel subjectively healthier. Some studies shown differences about SNPs gene Vietnamese. Therefore, it necessary study relationship between these habits leading diseases.